Compounds which pass through Prokaryotic cells

[phoenix0471]

Hi I'm doing research in the topic of antimicrobial Photodynamic therapy. I would like to know about the factors which determine different chemical compounds to enter into the cell wall of prokaryotic cells or which help it to stick on to the cell surface. About the hydrophilic, hydrophobic, lipophilic, cationic properties.

I'm more interested about the mechanisms that occur in gram negative bacteria