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karthik3k
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I want a list of Proteins of Unknown structure...
Where shall i find it ?
Where shall i find it ?
Find Proteins of Unknown Structure - Fast & Easy
- Thread starter karthik3k
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- Structure
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SUMMARY
The discussion focuses on locating proteins of unknown structure, emphasizing that most proteins indeed lack a determined 3D structure. The ExPASy Molecular Biology Server serves as the primary online repository for protein sequences, while the Protein Data Bank (PDB) is the go-to source for 3D protein structures derived from methods like x-ray crystallography and NMR. Users are advised to search for proteins in ExPASy and then verify their structural status in the PDB. Additional resources include the Scripps Metallo database for specialized protein information.
PREREQUISITES- Understanding of protein structure terminology (primary, secondary, tertiary, quaternary).
- Familiarity with the ExPASy Molecular Biology Server.
- Knowledge of the Protein Data Bank (PDB) and its usage.
- Basic concepts of protein determination methods such as x-ray crystallography and NMR.
- Explore the ExPASy Molecular Biology Server for protein sequence data.
- Investigate the Protein Data Bank (PDB) for available 3D structures.
- Research protein determination techniques like x-ray crystallography and NMR.
- Examine the Scripps Metallo database for specialized protein information.
Researchers in structural biology, bioinformaticians, and anyone involved in protein characterization and analysis will benefit from this discussion.