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Andy Resnick
Aug31-09, 02:57 PM
Sci Advisor
P: 5,539
Hang on, this is a bit more involved, I think.

Clearly, damaging the epidermal skin layer (which is mainly dead keratin) is different from triggering a sensory nerve. Apparently, one can produce a pain sensation by applying a localized electrical stimulus (Bishop, Physiol. Rev 26, 77-102, 1946), but I don't know if the specific mechanism has yet been elucidated.