Regenerative chemical turns muscle cells into stem cells

In summary, a group of researchers from The Scripps Research Institute has discovered a synthetic molecule, reversine, that can cause cells to undergo dedifferentiation and become multipotent precursor cells. This has the potential to provide an unlimited supply of precursors which can be converted into various cell types, such as bone or cartilage. This discovery could have significant implications in the field of stem cell research.
  • #1
fish
49
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found an interesting article on new stem cell research:

"La Jolla, CA. December 22, 2003—A group of researchers from The Scripps Research Institute has identified a small synthetic molecule that can induce a cell to undergo dedifferentiation—to move backwards developmentally from its current state to form its own precursor cell.

This compound, named reversine, causes cells which are normally programmed to form muscles to undergo reverse differentiation—retreat along their differentiation pathway and turn into precursor cells. These precursor cells are multipotent; that is, they have the potential to become different cell types. Thus, reversine represents a potentially useful tool for generating unlimited supply of such precursors, which subsequently can be converted to other cell types, such as bone or cartilage."

full article from Scripps Research Institute:
http://www.scripps.edu/news/press/122203.html
 
Biology news on Phys.org
  • #2
That's interesting, it is also known that some bloodcells are able to transform into braincells..
 
  • #3


This is a groundbreaking discovery in the field of stem cell research. The ability to induce dedifferentiation in muscle cells and turn them into multipotent stem cells has huge potential for regenerative medicine. This could potentially lead to new treatments for a variety of diseases and injuries, as well as providing a limitless source of stem cells for research purposes.

One of the most exciting aspects of this research is the potential for personalized medicine. By using a patient's own cells, there is less risk of rejection or adverse reactions. This could revolutionize the way we approach treatments for conditions such as muscular dystrophy or spinal cord injuries.

Of course, further research and clinical trials will be necessary to fully understand the capabilities and limitations of this technique. But this discovery opens up a whole new realm of possibilities for regenerative medicine and holds great promise for the future. It will be interesting to see how this research progresses and how it may impact the medical field in the coming years.
 

What is regenerative chemical?

Regenerative chemical is a substance that has the ability to stimulate the regeneration of tissue, organs, or cells in the body.

How does regenerative chemical turn muscle cells into stem cells?

Regenerative chemical can activate specific genes in muscle cells that are responsible for self-renewal and regeneration, essentially turning them into stem cells.

What are the potential benefits of using this regenerative chemical?

The use of this regenerative chemical could potentially lead to a limitless source of stem cells for therapeutic purposes, as well as aid in the repair and regeneration of damaged muscle tissue.

Are there any potential risks or drawbacks to using this regenerative chemical?

As with any medical treatment, there are potential risks and side effects associated with the use of this regenerative chemical. Further research and clinical trials are needed to determine its safety and effectiveness.

How long will it take for this regenerative chemical to be available for medical use?

The timeline for the availability of this regenerative chemical for medical use is dependent on the success of ongoing research and clinical trials. It could potentially take several years before it is approved for widespread use.

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