Difference Between GABA A and GABA B?

powerof1004

Pythagorean

In what sense?

At the molecular level, A receptors are Cl- ion channels, B receptors activate metabolic pathways. So A directly affects electrophysical properties, B affects molecular network dynamics through G protein cascades (which shut down the neuron's ion reactivity and down-regulates adenyl cyclase).

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powerof1004	Difference Between GABA A and GABA B? Difference Between GABA A and GABA B?

Pythagorean Recognitions: Gold Member	In what sense? At the molecular level, A receptors are Cl- ion channels, B receptors activate metabolic pathways. So A directly affects electrophysical properties, B affects molecular network dynamics through G protein cascades (which shut down the neuron's ion reactivity and down-regulates adenyl cyclase).