Is fish really brain food for developing children?

  • Medical
  • Thread starter rowkem
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In summary: what i've read, it seems like a lot of it is overdiagnosed and a lot of it is parents/doctors just looking for an excuse not to raise their kids.
  • #1
rowkem
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Be honest; isn't ADHD and all these "attention/behavioural disorders" a bunch of bull?

Needless to say, I'm not saying it doesn't exist. I'm sure years and years ago, people thought that schizophrenia and bipolar disorder was just an excuse but, isn't this a little to easily diagnosed? How much of this is real and how much is parents/doctors finding excuses as to why they can't raise their kids?
 
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  • #2
There is probably a lot of truth in what you say. I'm quite sure there are WAY too many children out there taking some form of Ritalin for their supposed ADHD.

However, what about adults who are now being diagnosed with ADHD/ADD? Some of them have suffered with it their whole lives and are just now learning how to deal with it. Many other things with similar symptoms (depression, thyroid disorders, menopause, hormone difficiencies...) have to be ruled out before it can be dx'd as ADHD/ADD.

I believe schizophrenia (now called MPD or Multiple Personality Disorder) and manic depression (now called bipolar disorder) are two different things. I know people with both of those disorders and they are not similar.
 
  • #3
MPD and bipolar are different conditions. The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) lists the standard nomenclature and diagnostics for them.

http://www.cdc.gov/ncbddd/adhd/symptom.htm lists diagnostic criteria for ADHD. Patients with problems like these are generally very ineffective at a broad range of common tasks. And looking at the criteria, it is easy to see why someone could be misdiagnosed. Or be diagnosed without necessarily having a problem.
 
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  • #4
rowkem said:
Needless to say, I'm not saying it doesn't exist. I'm sure years and years ago, people thought that schizophrenia and bipolar disorder was just an excuse but, isn't this a little to easily diagnosed? How much of this is real and how much is parents/doctors finding excuses as to why they can't raise their kids?
Having ADHD (and probably Asperger's or high functioning autism), I can tell it's no bull. My father and his father have ADD and my son has some level of it. It seems to run in families, and most of the time, those of us with it have to learn to cope. I self-mediated with caffeine. My son takes Concerta (slow releasing Ritalin) or he has difficulty staying on task.

Most parents of kids with ADD/ADHD try very hard to help there children function in society.
 
  • #5
I wasn't diagnosed with ADD until I was thirty. The reason I'm certain it's real in my case is that when I take Adderall, a Ritalin-like stimulant that treats it, my thought process changes radically. I normally can easily get completely lost in transitioning between any two thoughts or two steps in a process, but this doesn't happen when I'm on the Adderall. I'm able to accomplish any multi-step task in a fraction of the normal time if I'm on Adderall.

That said, what I've read agrees with you about ADD/ADHD being overdiagnosed. Also, from a personal perspective, I don't know that it would necessarily have been a good thing if I'd started taking a stimulant when I was a kid; at that point I don't think I was familiar enough with my own mental processes to have really understood the difference the drug makes. I might have gotten higher grades but meh, I don't care about that.

By the way, asking “isn't it a bunch of bull?” and then saying “I'm not saying it doesn't exist” is totally contradictory. It makes it look like you're trying to be provocative and conciliatory at the same time to avoid the effort of articulating a real opinion.
 
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  • #6
Who says it's a disorder?
I did a PhD in the theoretical astrophysics dept of a famous university. I would say that 50% of the students/staff could pass for normal with a bit of practice, 40% were definitely weird and 10% would have been institutionalised - if they weren't already effectively in one!
Start handing out Ritalain to the odd kids and you can say goodbye to any sicentists and programmers. And probably any arts - have a table Mr Beethoven and you will be able to play quietly!

My big objection is the diagnosis of dyslexia for anyone that didn't get a 4.0 GPA.
 
  • #7
i was tested for it, but diagnosed as negative.

however, i sometimes take ritalin or adderall from friends prescriptions for tests / exams, etc. (not all the time, just sometimes.)

and like posted above, it changes my thought process incredibly for the better, and i believe that better results come from it.

just because ritalin / adderall changes your thought process for the better, doesn't mean you have a disorder.

i'm not trying to deny that these disorders exist, because i haven't done enough research on the topic, but from my point of view i'll say that there are too many people diagnosed with add/adhd that don't actually have it.
 
  • #8
Full agreement with Astro on this. I was undiagnosed with ADD until I was about 46. It is very real and can be devastating.
 
  • #9
Its very real. And very comon that it runs in families. My son has it, but dosent take the meds for it, by his own choice. While they do keep him on task easier, they also make him depressed. He has learned to make lists and refur to them durring the day. He does not have the hyperactivity aspect of it.
We were able to trace it back several generations on my ex-husbands side of the family. Back in the 1940's it was called minimal brain disorder. They changed it to ADD in the 1960's, then added the ADHD in the 1970's.
 
  • #10
hypatia said:
We were able to trace it back several generations on my ex-husbands side of the family. Back in the 1940's it was called minimal brain disorder.

Were we married ?, maybe i got distracted and didn't find my way home:cry::biggrin:

Just found out about a year and a half ago, not quite sure how much the meds are helping, I'm one of the type, that has so many different interest and projects, that i work hard all the time and at the end of a day it is hard to define the progress in anyone area.
Making a list and sticking to it seems to never work, as something more important (and has to be done) almost always comes up.

Never have the big windfall, but there is always enough to get by on.:smile:
 
  • #11
I was put on Ritalin at age 7. I don't know if I ever got a formal ADHD diagnosis (actually I think they just called it "hyperactivity" back then). It was more of a "lets try some medication and see what happens" situation. A lot of it had to do with my 2nd grade teacher's annoyance with me, and I think it was at her insistence that I ended up getting taken to the pediatrician. I asked lots of questions in class and she found that irritating. School was pretty dull then because everyone in my class was just learning how to read, and I had been reading since before kindergarten. It's easy to be distracted when you are bored to tears.

So I ended up on Ritalin for a few months. It seemed to make me quiet and manageable, but I think my "zombification" scared my mom. So we stopped. I never gave up my taste for coffee and Coke, though. I was allowed to have caffeinated beverages in unlimited amounts and got hooked on them.

When third grade came around, I had a really nice teacher who loved teaching and loved inquisitive students. (She knew that second grade teacher I had, and didn't think much of her, btw.) Anyway, my third grade teacher kept me busy by giving me all the books I could read, and it was wonderful. She loved it when I asked questions! We moved away in the middle of the school year and I remember being in tears when I hugged my teacher goodbye.

I'll never know for sure if I had ADHD or was just a bored kid. I still wonder about it sometimes because I am a little impulsive and a bit of a scatterbrain. I usually work on four or five separate tasks simultaneously, jumping back and forth between open documents on my computer. Tiny noises completely dismantle my concentration. I've even quit a job because a co-worker's habit of humming and tapping made work impossible and my work hours unbearable. But all in all, I work around these things pretty well. Thank heavens for headphones.
 
  • #12
I was probably more ADD than ADHD, but I distinctly remember that I had a hard time sitting in my chair during elementary school through high school, except when the math and science instruction would go at a fast pace. Like Danger, I wasn't tested until about 45, when my son was tested. I was diagnosed with ADD (with symptoms of Asperger's and possibly high functioning autism), and my son is more ADHD. My son takes Concerta so that he can function in a way that is acceptable to the educational system.

I didn't take ritalin, but instead I self-medicated with caffeine (tea, then coffee) starting at about 12-13.

The worst time for me was taking a test (especially reading comprehension) in quiet room was pure torture.
 
  • #13
Firstly I am not trying to belittle anyones suffering.

But I am very suspicous of a sudden rise in purely psychometric diagnosis of what looks like bright kids/adults being bored in school. Even if you could do a decent diagnosis (involving some testable chemical/physical effect) isn't this just part of the range of behaviours / abilities people have?
Nobody diagnoses the football team with hyperactivity-running-disorder and proscribes sedatives to slow them down.

I can't see how prescribing psychoactive drugs to 6year olds just so that they will sit quietly in a boring lesson that is beneath their ability is a good idea.

Of course the fact that I have 20 windows open on 2 computers in front of me and I'm reading PF while dealing with a list of compiler errors mean I'm probably a sufferer.

(I await the flames from sufferers - although a medic interviewed about ME/yuppie-flu said he had a miracle cure, all he had to do was claim on TV that it didn't exist and 1000s of sufferers immediately lept from their beds to write in and complain! )
 
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  • #14
Yeah mgb_phys, I agree that ADD and many other things that are clinically called “disorders” are simply part of the range of behaviors and abilities that people have. And I think ADD is certainly overdiagnosed too. Which isn't the same thing as saying it's a “bunch of bull” but as I said I think the OP was going for a provocative headline.
 
  • #15
Astronuc said:
I was probably more ADD than ADHD, but I distinctly remember that I had a hard time sitting in my chair during elementary school through high school, except when the math and science instruction would go at a fast pace. Like Danger, I wasn't tested until about 45, when my son was tested. I was diagnosed with ADD (with symptoms of Asperger's and possibly high functioning autism), and my son is more ADHD. My son takes Concerta so that he can function in a way that is acceptable to the educational system.

How did they test you for ADD or ADHD? With me, they just went by the complaints from my teacher about my behavior. No tests involved, IIRC.
 
  • #16
Football players aren't diagnosed with any disorder because what they do is not disabling them on the sports field. For many people with ADD or ADHD their school or academic careers (and later careers) are threatened by their short attention spans. There may be misdiagnoses of bored school kids but that's due to the negligence of the doctor involved and shouldn't taint the fact that there are people unable to function correctly and are thus at a disadvantage. The reason things like this and Asperger's and Autism are coming to prominence is the fact that the medical community has recognised that these are real problems and are better at diagnosing them.
 
  • #17
Math Is Hard said:
With me, they just went by the complaints from my teacher about my behavior. No tests involved, IIRC.
So medical science has obviously progressed since medieval witch trials!
 
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  • #18
mgb_phys said:
So medical science has obviously progressed since medieval which trials!

While I'm not opposed to stimulants like Ritalin as attention-deficit therapy in some cases, I agree with you that there needs to be more care taken in diagnoses. In my situation, it was the 1970s, so I am hoping to hear that diagnostic methods have improved since then. There should be something more to it than the opinion of a possibly overwhelmed public school teacher who doesn't have time for the more enthusiatic and inquisitive students. Even if I did have a mild ADHD problem, drugs shouldn't have been the first choice for a solution.

On the other side of this, I have a little brother who has significant learning disabilities and was also diagnosed with ADD. Taking Adderall helped him a great deal with his concentration during classes, and he was able to complete high school. Most importantly, he thought the drug helped him, and wasn't averse to taking it. He doesn't take it anymore, but I think it helped get him through some rough spots while he was finishing school.

What disturbs me greatly are stories of Ritalin abuse in college students looking for that little extra edge:
http://www.azcentral.com/families/education/articles/0801back-ritalin-ON.html
Dr. Robert A. Winfield, director of University Health Service at the University of Michigan, Ann Arbor, sees a growing number of students who falsely claim to be ADHD sufferers so they can get a prescription. At least once a week, a jittery, frightened, sleep-deprived student who has taken too many tablets for too many days shows up at his office. "Things have really gotten out of hand in the last four to five years," he said. "Students have become convinced that this will help them achieve academic success."
 
  • #19
Math Is Hard said:
There should be something more to it than the opinion of a possibly overwhelmed public school teacher who doesn't have time for the more enthusiatic and inquisitive students.

One key diagnostic criterion that should be considered is that the problem is NOT situational. If a kid ONLY has trouble sitting still/paying attention in class, but can focus on tasks at home, or during afterschool activities, it is more likely they are just plain bored with school and not that they have ADD or ADHD. If a kid seems "scatter-brained" about everything they do, flitting from one task to another, never completing things, never staying focused long, then there is a better justification for further consideration of ADD or ADHD (among other things that should be ruled out) as a diagnosis.

Others have pointed it out, and it bears emphasizing that MISdiagnosis doesn't mean the disorder isn't real and doesn't exist in other people. The more I think about it, I really don't like the term OVER-diagnosis, because who sets the quota on how many diagnoses are allowed to be real before we decide it's all a "bunch of bull" as the OP put it? It simply could be that more kids are diagnosed because more physicians are aware there is a name for this behavior and there is a treatment for it too.

I do suspect there are a lot of misdiagnosed kids out there because people have NOT taken the time to fully evaluate their symptoms, the context of their symptoms, and to rule out other explanations for them. Your average general practitioner is NOT a specialist in pediatric psychiatry, and should not be the one making the final diagnosis of such disorders, but rather should be acting as a gatekeeper, saying that a particular kid meets some general criteria that merit further evaluation by a specialist. It is quite possible that normal, active, creative children are being MISdiagnosed because parents and teachers are pushing to have their lives made easier rather than learning to raise an active, creative child, but that certainly doesn't mean there aren't really people with ADD or ADHD.

If you read the older literature (I may have cited those references in much older posts here, but don't feel like looking them all up again), the diagnostic criteria are much stricter and narrower than the commonly found "if you or your child has more than 4 of these symptoms" type checklists often used to make a diagnosis today.
 
  • #20
MIH said:
"lets try some medication and see what happens" situation
That's something you could say about the current state of psychiatric treatment altogether.
 
  • #21
Math Is Hard said:
How did they test you for ADD or ADHD? With me, they just went by the complaints from my teacher about my behavior. No tests involved, IIRC.

Yes, I've had my son's home room teacher prescribing ritalin for him. I was this close to getting her fired for practicing psychiatry without a license. But, instead I bought him this stuff... people lacking the ability to attend to task might want to "experiment" with "brain food". Dr. Mik Lions studied many cases of ADD and ADHD (or whatever someone likes to call it) and found that in most cases the condition and behaviours were caused by mal-nutrition. Specifically nutrition that bolsters neuronal development and function.

Here's a link to "Natural Factors" in the U.S.A. http://us.naturalfactors.com/ it is a company that hired Dr. Lions to register, trademark and produce his nutritional supplement they call "learning factors".

http://us.naturalfactors.com/search.asp

My son blew the doors off of that elementary class... about 2 days after starting the supplement. His marks went sky high and his behaviour straightened out like an arrow. The home room teacher was aghast and amazed at the change... thinking we had put him on ritalin like she so professionally recommended (not).

I told her it was the learning factors® making the change and that she should stick to curriculum or have her teaching certificate revoked.

I recommend that anyone willing to give this supplement a try to use the smoothie mix. If anyone wants a break-down on how to make the smoothie with the powder... please ask for it from me on this page. Thank you.
 
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  • #22
Moonbear said:
The more I think about it, I really don't like the term OVER-diagnosis, because who sets the quota on how many diagnoses are allowed to be real before we decide it's all a "bunch of bull" as the OP put it? It simply could be that more kids are diagnosed because more physicians are aware there is a name for this behavior and there is a treatment for it too.

Presumalbly it is also due to the fact that kids nowadays are under much more pressure to do well in school. Until just a few decades ago it was possible to get a good job without any academic merits as long as you were good at "practical" work. E.g. a carpenter's apprentice could look forward to quite a well paid job and the training was really "hands on".
Nowadays that is much more difficult meaning both students and teachers are under much more pressure to make sure that EVERYONE has at least some "basic" skills (skills that just 100 years ago would have meant that you were really well educated) and this means that conditions like dyslexia, ADHD etc become much more visible.
 
  • #23
baywax said:
Yes, I've had my son's home room teacher prescribing ritalin for him. I was this close to getting her fired for practicing psychiatry without a license. But, instead I bought him this stuff... people lacking the ability to attend to task might want to "experiment" with "brain food". Dr. Mik Lions studied many cases of ADD and ADHD (or whatever someone likes to call it) and found that in most cases the condition and behaviours were caused by mal-nutrition. Specifically nutrition that bolsters neuronal development and function.

Malnutrition IS NOT ADD or ADHD. But, that's what I mean about misdiagnosis. One needs to rule out things like malnutrition, insufficient sleep, simple boredom, allergies, and a whole host of other reasons someone might have trouble paying attention before it can be called ADD or ADHD. We know that malnutrition hinders learning, and this is the reason why we have free or reduced cost school lunch programs (and breakfast programs in some schools) to ensure kids get at least one nutritious meal a day. Given all the junk food kids eat, it wouldn't surprise me if there are a lot more malnourished yet surprisingly chubby kids running around today compared with when I was a kid, and that those kids would have difficulty paying attention in school. True ADD or ADHD will not improve with simple dietary changes, getting more sleep at night, etc.
 
  • #24
Moonbear said:
It is quite possible that normal, active, creative children are being MISdiagnosed because parents and teachers are pushing to have their lives made easier rather than learning to raise an active, creative child, but that certainly doesn't mean there aren't really people with ADD or ADHD.

Hi MB,
I figure this comment probably wasn't directed specifically at me, but I just want to clarify that I wasn't suggesting that ADD and ADHD are not genuine disorders. As I was saying, the medication was not a solution for me, but it was very helpful for my brother.

If you read the older literature (I may have cited those references in much older posts here, but don't feel like looking them all up again), the diagnostic criteria are much stricter and narrower than the commonly found "if you or your child has more than 4 of these symptoms" type checklists often used to make a diagnosis today.

I am going to look into that. I'm curious about what diagnostic tools are available now. Maybe there is a standard battery of questions that are used (something like the Beck Depression Inventory, I'm assuming).
 
  • #25
Moonbear said:
Malnutrition IS NOT ADD or ADHD. But, that's what I mean about misdiagnosis. One needs to rule out things like malnutrition, insufficient sleep, simple boredom, allergies, and a whole host of other reasons someone might have trouble paying attention before it can be called ADD or ADHD.
If I were an epidemiologist looking to make a mark, I would study the air quality in schools and chart the incidence of ADD and asthma. How can children whose neurological systems and respiratory systems are still developing be expected to go to school every day and breath a toxic soup of fragrance chemicals, chemicals from cleaning products, including masking fragrances like those in Febreze and others and NOT be affected. Most of those little kids are dressed up in clothes saturated in scented fabric softeners, and when they go home, their mother's got some scented candles lit, with a Glade plug-in in the bathroom and the kitchen. It's too much. Here's a few quick links.

http://www.chebucto.ns.ca/education/CASLE/fragrance.html
http://www.geocities.com/fragranceallergy/facts.html
http://mcs-america.org/fragrancefacts.pdf
 
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  • #26
Turbo, have you read http://www.ameliaww.com/fpin/fragrance_rti4948.htm"
 
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  • #27
I lived my life to age 63 before ever hearing the meaning of ADD, and OCD. Having grandchildren that were determined as having ADD, i was introduced to this knowledge, through the book "Driven To Distraction".
My life for the most part, has been somewhat successful, and fun, but there has always been a lack of something that i could not understand, i thought it was an inability to develop good habits, and discipline, and a compulsive desire to collect anything because i might need it, (i blamed it on a poverty childhood) having parents that lived thru the depression and WWII, we moved to Arkansas in the 40's.
Almost all the flags that are looked for, you will find in my life. When i saw in the book, a lot of problems, and solutions that other people identified, there was such a flood of relief that, it is hard to explain. It has been about 18 Months, some medicines have had no effect, i stopped for about 6 months, and now have just started a increase in Ritalin.
Lack of food or improper diet is not a problem in my case, nor my grand children.

The meds alone will not be my solution, but i know the problem is real, and i see a little hope that my last years will be a bit more productive.
 
  • #28
Moonbear said:
. True ADD or ADHD will not improve with simple dietary changes, getting more sleep at night, etc.

Hi Moonbear. I was perhaps simply reacting to Math Is Hard's predicament where pure heresay, opinion and no tests may have resulted in more sales for the makers of Ritalin. My son does not have Attention Deficit nor does he suffer from A Deficit of Attention. In fact he's on the math honor roll now.

Are there any studies or papers that back your claim? [edit] These aren't simple dietary changes. Have a look at the list of ingredients.
 
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  • #29
I assume so...

rowkem said:
Needless to say, I'm not saying it doesn't exist. I'm sure years and years ago, people thought that schizophrenia and bipolar disorder was just an excuse but, isn't this a little to easily diagnosed? How much of this is real and how much is parents/doctors finding excuses as to why they can't raise their kids?


Well, schizophrenia is a BIG subject to talk about, (later , no time)

But ADHD has been proven to be a disorder.

There is actually a big branch about ADHD in psychology.

It affects the brain as well as the childs behavior.

Einstienear
 
  • #30
chemisttree said:
Turbo, have you read http://www.ameliaww.com/fpin/fragrance_rti4948.htm"
Thanks! I've got that rascal bookmarked somewhere, but since I've got pages of these links, It's not easy to find one or two when you're posting in a thread. My experience with gas chromatography is limited to detecting potent sulfur compounds in paper mill effluent, and the detection/quantification ability was highly sensitive to column length and temperature. I am here to testify that hydrogen sulfide is a baby-player, as is methyl sulfide. Tiny exposures to dimethyl sulfide and dimethyl disulfide (and others) could earn you a single corner table at the cafeteria, come lunchtime.
 
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  • #31
Here's a site with links to studies on Nutrition and ADD showing detrimental and beneficial effects of diet as related to the disorder.

http://www.feingold.org/Research/adhd.html

This one specifically compared Ritalin to Food Supplements with regard to benefits. Both treatments faired well.

Outcome-based comparison of Ritalin versus food-supplement treated children with AD/HD. Harding KL, Judah RD, Gant C. Altern Med Rev. 2003 Aug; 8(3): 319-30.
" Twenty children with attention deficit/hyperactivity disorder (AD/HD) were treated with either Ritalin (10 children) or dietary supplements (10 children) . . . Subjects in both groups showed significant gains . . . . . .Numerous studies suggest that biochemical heterogeneous etiologies for AD/HD cluster around at least eight risk factors: food and additive allergies, heavy metal toxicity and other environmental toxins, low-protein/high-carbohydrate diets, mineral imbalances, essential fatty acid and phospholipid deficiencies, amino acid deficiencies, thyroid disorders, and B-vitamin deficiencies. . . . These findings support the effectiveness of food supplement treatment in improving attention and self-control in children with AD/HD and suggest food supplement treatment of AD/HD may be of equal efficacy to Ritalin treatment. "

If someone is going to try the smoothie mix, here's the effective Smoothie receipt:

1 ounce of Apple Juice around the blades of the blender

4 ounces of 6 to 18 percent milk fat Yogurt Plain on top

add 2 servings of Learning Factors supplement

Run blender until powder and yogurt and juice are mixed up

add bio-active type yogurt, raspberry or blueberry or mixed...

to the near the top... leave room for 2 or 3 bananas and half an apple... unpeeled.

Turn blender on high until completely blended.

serves about four cups...

(edit: apple unpeeled not the bananas;)
 
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  • #32
baywax said:
Here's a site with links to studies on Nutrition and ADD showing detrimental and beneficial effects of diet as related to the disorder.

http://www.feingold.org/Research/adhd.html

This one specifically compared Ritalin to Food Supplements with regard to benefits. Both treatments faired well.

There were only 10 kids per treatment group in that study. That's not a large enough sample size to have any power to detect differences. They probably fared equally well because they had no statistical power to detect differences even if they existed.

That journal is rather light on scientists (lots of doctors of naturopathic medicine, some MDs...MDs are not trained to evaluate research studies...and a couple PhDs) in their editorial review board, which suggests to me they are not a particularly reputable journal.
 
  • #33
Math Is Hard said:
How did they test you for ADD or ADHD? With me, they just went by the complaints from my teacher about my behavior. No tests involved, IIRC.
My son and I were interviewed by a psychologist, and we took a computer based test that has some kind of a repetitive test. At this stage of my life, I'm borderline, i.e. I've managed to compensate for the most part. My son on the other hand is ADD (borderline ADHD). He takes Concerta, and that makes all the difference. Without Concerta, he has a hard time functioning 'normally'.
 
  • #34
Moonbear said:
There were only 10 kids per treatment group in that study. That's not a large enough sample size to have any power to detect differences. They probably fared equally well because they had no statistical power to detect differences even if they existed.

That journal is rather light on scientists (lots of doctors of naturopathic medicine, some MDs...MDs are not trained to evaluate research studies...and a couple PhDs) in their editorial review board, which suggests to me they are not a particularly reputable journal.

Here's a broader study from the Global Neuroscience Initiative Foundation, Los Angeles, CA, USA. slakhan@gnif.org.

And here's an excerpt related to the topic of this thread...

Studies have shown that daily supplements of vital nutrients often effectively reduce patients' symptoms. Supplements that contain amino acids also reduce symptoms, because they are converted to neurotransmitters that alleviate depression and other mental disorders. Based on emerging scientific evidence, this form of nutritional supplement treatment may be appropriate for controlling major depression, bipolar disorder, schizophrenia and anxiety disorders, eating disorders, attention deficit disorder/attention deficit hyperactivity disorder (ADD/ADHD), addiction, and autism.

Thank you : - )


http://www.ncbi.nlm.nih.gov/pubmed/...ez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
 
  • #35
baywax said:
Here's a broader study from the Global Neuroscience Initiative Foundation, Los Angeles, CA, USA.
Broader in what way? It's not even a study, but a review article, and doesn't address ADD or ADHD at all. Did you read the article? It's not supporting your claim at all, but rather suggesting some nutrient supplements can help alleviate symptoms, but do not eliminate the disorder.

For example, they say:
Double-blind, placebo controlled studies, randomized, placebo controlled studies, and open-label clinical studies have all shown that approximately 2 g of EPA taken daily in addition to one's existing medication effectively decreases symptoms in schizophrenic patients [59,60,65].

Regarding the above statement, reference 59 is another review article. Reference 60 is a randomized, double-blind, placebo-controlled study, but only enrolled 40 patients (20 per group). Again, this is a very weak design for a clinical trial.

http://ajp.psychiatryonline.org/cgi/content/full/159/9/1596

And, conveniently, the ONLY OTHER clinical trial testing the same thing with a larger enrollment was left out of the references...the one that says there's NO effect:
http://ajp.psychiatryonline.org/cgi/content/full/158/12/2071

Reference 65 is an open-label clinical trial with only 12 patients enrolled! That's about as good as worthless. And, it wasn't even measuring schizophrenia symptoms, but merely serotonin binding to platelets.
http://www.ncbi.nlm.nih.gov/pubmed/15253886There are also some glaring errors in this paper.
As an example, they state:
Two double-blind, placebo-controlled studies were recently performed that compared the affects of a 900 mg daily dose of St. John's wort extract to 20 mg daily doses of Paroxetine (Paxil) or Fluoxetine; which are both SSRIs used to treat OCD. In comparison to patients taking Paxil, those who took the St. John's wort supplement showed a 57% decrease in OCD symptoms and were 47% less likely to exhibit side effects [69].

Except, when you look up the reference they cited, once you sort out that their citation in the reference list is for the erratum, not the original study and backtrack to the original study, you find out that the cited paper did NOT study OCD, but depression, and didn't find that St. John's wort was better than Paxil, but that it was equally effective (this is really no surprise...St. John's wort has been known for some time to have real pharmacological efficacy for depression with the only major concern regarding herbal supplements containing it being 1) that patients are self-medicating rather than getting a proper diagnosis before taking a pharmacological agent, and 2) that doses are not consistent in herbal supplements and not regulated to ensure consistency. The percent decrease in symptoms was from baseline, not relative to Paxil, so the above cited article grossly misleads the reader to think there is a greater effect than actually described (this is why it's important to read critically and not take one single author's word...dig up the articles they are citing and see if you come to the same conclusions or if they are being accurately cited).

More importantly, regarding the argument you're trying to make, that's not addressing a nutrient deficiency, but using an herbal supplement to provide a pharmacologically active compound.

http://www.bmj.com/cgi/content/abstract/330/7490/503
and the erratum
http://www.bmj.com/cgi/content/full/330/7494/759-a

In fact, each of their major conclusions is riddled with errors.

Randomized, controlled trials that involve folate and B12 suggest that patients treated with 0.8 mg of folic acid/day or 0.4 mg of vitamin B12/day will exhibit decreased depression symptoms [9].
Tracking down reference 9, it is NOT a randomized, controlled trial, it is an EDITORIAL!

And what was reference 9 ACTUALLY commenting about? This:
A recent metaanalysis looked at the results of 25 randomized controlled trials of folate supplements in people who were not selected because of low folate levels. The conclusion was that daily dosages of 0.8 mg folic acid or more, in addition to dietary intake, are typically required to achieve the maximal reduction in plasma homocysteine concentrations (about 25%).17 Vitamin B12 (0.4 mg/day) produced a further 7% reduction.
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17353937

Not a dang thing about depression there, they're talking about homocysteine levels.
And why were the homocysteine levels being compared in the meta-analysis (note that you have to dig back three levels of references from the one cited to even get to a randomized clinical trial...one is an editorial, the next a meta-analysis, and finally one will get to the actual clinical trials).
Background: Dietary supplementation with B vitamins that lower blood homocysteine concentrations is expected to reduce cardiovascular disease risk, but there has been uncertainty about the optimum regimen to use for this purpose.
http://www.ajcn.org/cgi/content/full/82/4/806

Wow, the more I check their references, the more shockingly incorrect I find each and every statement I follow up! If this is indicative of the usual articles within this journal, it cannot be very reputable.
 
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