Diabetes & Glucagon: Why Do Levels Rise?

  • Thread starter goingmad
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In summary, diabetes is a chronic disease that affects the body's ability to process glucose, leading to high blood sugar levels. This can be caused by a lack of insulin production or resistance to its effects. Glucagon, a hormone produced by the pancreas, plays a role in regulating blood sugar levels and can become imbalanced in people with diabetes. High levels of glucagon can lead to hyperglycemia and serious complications if left untreated. Managing diabetes through lifestyle changes and medication can help control glucagon levels and maintain stable blood sugar levels.
  • #1
goingmad
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Why is it the case that glucagon levels actually rise during diabetes? This seems to be what's implied everywhere I look. What causes the rise? Is it more accurate to say that all the metabolic things that start happening with untreated diabetes is because of the drop in the insulin:glucagon ratio in general? Is it even the case that glucagon levels rise?
I'm so confused about this!
Thanks,
 
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  • #2
Try Wiki. They have a pretty good summary.
 
  • #3
This site may also help you understand how it works.

http://www.deo.ucsf.edu/type1/understanding-diabetes/how-the-body-processes-sugar/blood-sugar-and-other-hormones.html
 
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1. What is diabetes?

Diabetes is a chronic disease that affects how your body processes glucose, also known as blood sugar. There are two main types of diabetes: type 1 and type 2. In type 1 diabetes, the body does not produce enough insulin, a hormone that helps regulate blood sugar levels. In type 2 diabetes, the body either doesn't produce enough insulin or becomes resistant to its effects.

2. What is glucagon and how does it relate to diabetes?

Glucagon is a hormone produced by the pancreas, which helps regulate blood sugar levels. It has the opposite effect of insulin, as it raises blood sugar levels by signaling the liver to release stored glucose into the bloodstream. In people with diabetes, there may be an imbalance between insulin and glucagon, leading to high blood sugar levels.

3. Why do glucagon levels rise in people with diabetes?

In people with type 1 diabetes, the pancreas does not produce enough insulin, so the body may rely on glucagon to raise blood sugar levels. In type 2 diabetes, the body may become resistant to the effects of insulin, causing the pancreas to produce more glucagon. Additionally, certain medications used to treat diabetes may also increase glucagon levels.

4. How does high glucagon levels affect people with diabetes?

High glucagon levels can lead to hyperglycemia, or high blood sugar levels. This can cause symptoms such as increased thirst, frequent urination, fatigue, and blurred vision. If left untreated, high blood sugar levels can lead to serious complications such as nerve damage, kidney disease, and cardiovascular disease.

5. What can be done to control glucagon levels in people with diabetes?

Managing diabetes through a combination of lifestyle changes, such as a healthy diet and regular exercise, and medication can help control glucagon levels. Insulin therapy and certain diabetes medications can also help to regulate glucagon levels and maintain stable blood sugar levels. It is important for people with diabetes to work closely with their healthcare team to develop an individualized treatment plan that addresses their specific needs.

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