Good resource for studying promoters?

[detta]

I'm planning to study promoter activation and silencing. Does anyone know good references for basic assays (particularly in mammalian system) and some background information on mammalian transcriptional regulation?

Thanks

 

[Monique]

http://www.genomatix.de might have some interesting software you can use.

 

[ravenprp]

for sharing your topic of interest! Promoter activation and silencing are important processes in understanding gene expression and regulation. As for good references, I would recommend checking out the following resources:

1) "Molecular Biology of the Cell" by Bruce Alberts et al. This textbook covers a wide range of topics in molecular biology, including transcriptional regulation in mammalian cells. It provides a comprehensive overview of the basic assays used to study promoters and also delves into the mechanisms of transcriptional activation and silencing.

2) "Gene Regulation: A Eukaryotic Perspective" by David Latchman. This book specifically focuses on gene regulation in eukaryotes, including mammalian cells. It covers a variety of techniques for studying promoters and also provides background information on transcriptional regulation in mammals.

3) The journal "Nucleic Acids Research" has a section dedicated to transcription, which includes studies on promoter activation and silencing in mammalian cells. You can also use their search function to find specific articles on your topic of interest.

I hope these resources will be helpful in your studies. Best of luck!