Is there any study about how enzyme work on level atom

In summary, there have been many studies on how enzymes work at the atomic level, using techniques such as x-ray crystallography, NMR spectroscopy, and electron microscopy. These studies reveal the structure of enzymes and their catalytic mechanisms, and can be further analyzed using computer simulations. Information about enzyme catalysis and structural studies can be found in biochemistry textbooks and on the Protein Data Bank website.
  • #1
markone2
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Is there any study about how enzyme work on level atom ?
where i can read about subject ?
 
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  • #2
There has been a lot of work about how enzymes work at the atomic level. Most studies have used x-ray crystallography (and increasingly NMR spectroscopy and electron microscopy) to determine the three-dimensional structures of enzymes at atomic resolution. These pictures of enzymes can help reveal which parts of the enzyme are involved in performing catalysis and reveal regulatory mechanisms. Using these enzyme structures, biologists can then study enzyme catalysis computationally using molecular dynamics or other types of computer simulations.

Most biochemistry textbooks should talk about enzyme catalysis and mention structural studies of enzymes. The Protein Databank (http://www.rcsb.org/pdb) is a repository for atomic resolution structures of proteins, and it's molecule of the month feature talks about many enzymes and how they work.
 
  • #3


Yes, there have been numerous studies conducted on how enzymes work on an atomic level. Enzymes are complex proteins that catalyze biochemical reactions in living organisms, and their function is dependent on their specific atomic structure. Scientists have used various techniques, such as X-ray crystallography and nuclear magnetic resonance spectroscopy, to study the atomic structure of enzymes and understand their mechanism of action. Additionally, computational methods have also been utilized to simulate enzyme reactions at the atomic level. You can find more information about these studies in scientific journals and textbooks on biochemistry and enzymology.
 

1. What is an enzyme?

An enzyme is a type of protein that acts as a biological catalyst in chemical reactions. It speeds up the rate of a reaction without being consumed in the process.

2. How does an enzyme work on a molecular level?

Enzymes work by binding to specific molecules, called substrates, in order to facilitate a chemical reaction. They do this by lowering the activation energy needed for the reaction to occur, making it easier for the reaction to take place.

3. Is there any research on how enzymes work on an atomic level?

Yes, there have been numerous studies on the atomic structure and mechanisms of enzymes. Scientists use techniques such as X-ray crystallography and nuclear magnetic resonance (NMR) to study the structure and function of enzymes at the atomic level.

4. What factors affect the activity of enzymes?

Several factors can affect the activity of enzymes, including temperature, pH, substrate concentration, and the presence of inhibitors or activators. Enzymes have an optimal range for these factors, and any deviations can impact their activity.

5. Why is it important to understand how enzymes work on an atomic level?

Understanding the atomic mechanisms of enzymes is crucial in fields such as medicine, biotechnology, and environmental science. It allows scientists to design and optimize enzymes for specific purposes, as well as develop new drugs and treatments for diseases.

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