Why does haemotocrit decrease in acute blood loss?

In summary, haemotocrit levels decrease in acute blood loss due to a decrease in the amount of red blood cells in the blood. The normal range for haemotocrit levels varies, but is generally between 40-52% for men and 35-47% for women. The body compensates for a decrease in haemotocrit levels by increasing the production of red blood cells and releasing stored red blood cells from the spleen. Other causes of a decrease in haemotocrit levels include chronic diseases, nutritional deficiencies, and certain medications. A decrease in haemotocrit levels can be diagnosed through a complete blood count (CBC) test.
  • #1
sameeralord
662
3
In acute blood loss both RBC and fluid is lost, so why doesn't haemotocrit stay normal. I know compensatory mechanism would increase the fluid, eg kidney. But red blood cell prodcution would take few weeks. Is that the reason haemotocrit decreases? Thanks :smile:
 
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  • #2
Indeed. Plasma would be restored way before RBC count.
 
  • #3
The decrease in mechanical pressure results in a reballance of intersititial fluid (eg think the opposite of edema).
 

1. Why does haemotocrit decrease in acute blood loss?

Haemotocrit is the percentage of red blood cells in the total blood volume. When there is acute blood loss, the amount of red blood cells in the blood decreases, leading to a decrease in haemotocrit levels. This is because red blood cells are responsible for carrying oxygen to different parts of the body, and the loss of red blood cells means less oxygen can be transported.

2. What is the normal range for haemotocrit levels?

The normal range for haemotocrit levels varies depending on age, gender, and other factors. In general, the normal range for men is between 40-52%, and for women is between 35-47%. These levels may vary slightly between different laboratories, so it is important to consult with a healthcare provider for an accurate interpretation of haemotocrit levels.

3. How does the body compensate for a decrease in haemotocrit levels?

When there is a decrease in haemotocrit levels, the body will compensate by increasing the production of red blood cells in the bone marrow. This process is called erythropoiesis. The body may also release stored red blood cells from the spleen to help maintain adequate levels of red blood cells in the blood.

4. What are the causes of a decrease in haemotocrit levels other than acute blood loss?

Other than acute blood loss, a decrease in haemotocrit levels can be caused by chronic diseases such as anemia, nutritional deficiencies, bone marrow disorders, and certain medications. It can also be a symptom of underlying health conditions like kidney disease or cancer.

5. How is a decrease in haemotocrit levels diagnosed?

A decrease in haemotocrit levels can be diagnosed through a simple blood test called a complete blood count (CBC). This test measures the levels of red blood cells, white blood cells, and platelets in the blood, including haemotocrit levels. A CBC test is often ordered if there are signs or symptoms of anemia or if there is suspected blood loss.

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