Antibacterial Soap: How Trichlorocarbanilide Kills Bacteria

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In summary, trichlorocarbanilide kills bacteria by increasing the permeability of the cell membrane, disrupting cell function by interfering with the regulation of chloride and hydroxide ions. A good source for more information on its biological modes of action is PubMed.
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chound
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How exactly does trichlorocarbanilide kill bacteria?
 
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For biological modes of action, a good place to look is PubMed

Here is an example reference
 
  • #3
Ouabache said:
For biological modes of action, a good place to look is PubMed

Here is an example reference
He might have been hoping for a slightly less technical (or more plain English) answer. :wink: A quick reading of that reference sounds like it works by increasing the permeability of the cell membrane to chloride and hydroxide ions to disrupt cell function (since the cell can't regulate those ions properly in the presence of trichlorocarbanilide).

If someone would like an explanation more intermediate between the very simplified one I provided and the very technical one in the article Ouabache linked to, ask away!
 
  • #4
No I need a technical answer
 

1. How does trichlorocarbanilide (TCC) kill bacteria in antibacterial soap?

TCC is a synthetic compound that works by disrupting the bacterial cell membrane, causing the cell to leak and eventually die.

2. Is TCC safe to use in antibacterial soap?

Studies have shown that TCC is generally safe for use in antibacterial soap, but there are concerns about its potential to contribute to antibiotic resistance.

3. Can bacteria become resistant to TCC?

While there have been some reported cases of bacteria developing resistance to TCC, it is not as common as with other antibacterial agents.

4. How effective is TCC against different types of bacteria?

TCC has been found to be effective against a wide range of bacteria, including both gram-positive and gram-negative bacteria.

5. Does using antibacterial soap with TCC lead to a decrease in healthy bacteria on the skin?

There is some evidence that suggests using antibacterial soap with TCC may disrupt the balance of bacteria on the skin, but more research is needed to fully understand the effects.

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