How to Determine if a Molecule is Optically Active

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In summary, determining whether a molecule is optically active can be done through two main tests. The first is to create a model and see if its mirror image can be superimposed on it. If it can, the molecule is not optically active. The second test is to look for a chiral atom, which is an atom with all different attached groups. If there is only one chiral atom, the molecule is optically active, but if there are multiple chiral atoms, further tests may be needed.
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nemzy
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how do we know if a molecule is optically active?

does it have to do something about R,S configurations? I have no idea, what it is...and how to know whether a molecule is optically active or not

thanks
 
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The only sure test to see whether a molecule is optically active or not is to make a model and see whether its mirror image is super-imposable on it or not. If it is superimposable, it's not optically active.

Another good but not sure test is to search for a chiral atom, i.e, an atom with all groups attached to it being different. If the molecule has only one chiral atom, it is sure to be optically active, but if it has more than one chiral atoms, you will have to perform other tests.
 
  • #3
vinter said:
The only sure test to see whether a molecule is optically active or not is to make a model and see whether its mirror image is super-imposable on it or not. If it is superimposable, it's not optically active.

That would be superposable, not superimposable. Any two things can be superimposed, but not everything can be superposed :-)
 

1. What are optically active compounds?

Optically active compounds are molecules that have the ability to rotate the plane of polarized light. This means that when polarized light passes through the compound, the light is bent in a specific direction. This property is due to the asymmetrical arrangement of atoms in the molecule, which causes the compound to have a chiral or non-superimposable mirror image.

2. How do optically active compounds affect polarized light?

Optically active compounds interact with polarized light by rotating its plane of polarization. This means that the light waves are bent in a specific direction as they pass through the compound, resulting in a change in the angle of the light waves. The amount of rotation is dependent on the specific compound and its concentration in a solution.

3. What is the difference between a chiral and an achiral molecule?

A chiral molecule is one that has a non-superimposable mirror image, meaning that the molecule and its mirror image are not identical. This results in chirality or handedness, which gives the molecule the ability to rotate the plane of polarized light. An achiral molecule, on the other hand, has a superimposable mirror image and therefore does not exhibit optical activity.

4. How are optically active compounds used in everyday life?

Optically active compounds have a variety of uses in everyday life. They are commonly used in the pharmaceutical industry to create drugs that have specific effects on the body. They are also used in the food industry to create artificial flavors and fragrances. Optically active compounds are also used in the production of LCD screens, as well as in the manufacturing of polarizing sunglasses.

5. Can optically active compounds be separated from their mirror images?

Yes, optically active compounds can be separated from their mirror images through a process called enantiomer separation. This involves using techniques such as chromatography or crystallization to physically separate the two forms of the compound. Enantiomer separation is important in the pharmaceutical industry, as it allows for the production of drugs with specific effects and fewer side effects.

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