Can we create artificial macrophages?

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In summary, the question is if it is possible to create a tablet with macrophages to fight off viruses. The answer is probably not due to challenges in getting the phages absorbed into the body and the difficulty in custom building them for each individual. Other options such as injecting them like a vaccine could also face complications with the body's immune response.
  • #1
sameeralord
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This might be a cheesy question. If Macrophages can ingest virus, can't we create a tablet with macrophages and take it when we want to fight off virus. Would this work?
 
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  • #2
Interesting question: My guess is, probably not. The first challenge would be to get those phages absorbed into the body. The GI track is pretty good at breaking simple organic substances down to simpler absorbable molecules. The phages would either be completely dissolved or would pass thru the intestines.

Another option would be to bypass the gastric acids and inject them, like a vaccine. If the proteins that made up the artificial macrophages weren't a perfect match with the host body, then the body would believe it was under a second attack and would fight against the macrophages..

Each artificial phage would have to be custom built for each person. That would probably put it out reach, technically.
 
  • #3
Louiswap said:
Interesting question: My guess is, probably not. The first challenge would be to get those phages absorbed into the body. The GI track is pretty good at breaking simple organic substances down to simpler absorbable molecules. The phages would either be completely dissolved or would pass thru the intestines.

Another option would be to bypass the gastric acids and inject them, like a vaccine. If the proteins that made up the artificial macrophages weren't a perfect match with the host body, then the body would believe it was under a second attack and would fight against the macrophages..

Each artificial phage would have to be custom built for each person. That would probably put it out reach, technically.

Oh I see thanks for your time Louiswap :smile:
 

1. Can we create artificial macrophages and if so, what are they?

Yes, scientists have been working on creating artificial macrophages, which are synthetic versions of the immune cells found in the human body. These artificial macrophages are designed to mimic the functions of natural macrophages, such as identifying and destroying harmful substances in the body.

2. What are the potential applications of artificial macrophages?

Artificial macrophages have the potential to be used in various medical applications, such as targeted drug delivery, cancer treatment, and tissue engineering. They can also be used in environmental remediation to remove pollutants and toxins.

3. How are artificial macrophages created?

There are different approaches to creating artificial macrophages, but most involve using materials such as liposomes, nanoparticles, or hydrogels to mimic the structure and functions of natural macrophages. Some methods also involve incorporating biological components, such as proteins, into the artificial macrophages.

4. What are the challenges in creating artificial macrophages?

One of the main challenges in creating artificial macrophages is replicating the complex functions and interactions of natural macrophages. Another challenge is ensuring that the artificial macrophages are safe and effective for use in medical treatments.

5. What progress has been made in the development of artificial macrophages?

While there is still much research and development needed, scientists have made significant progress in creating artificial macrophages. Some studies have shown that these synthetic immune cells can effectively target and destroy cancer cells in mice, and researchers continue to work on improving their functionality and potential applications.

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