When Science and computer gamers collide

In summary, online gamers have successfully deciphered the structure of an enzyme of an AIDS-like virus, which had been a challenge for scientists for a decade. This feat was achieved through the use of a video game called Foldit, where gamers compete to unfold chains of amino acids. The gamers were able to produce an accurate model of the enzyme in just three weeks, providing new insights for the design of antiretroviral drugs. This collaboration between gamers and scientists shows the potential for combining gaming, science, and computation to solve complex problems.
  • #1
rhody
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http://articles.timesofindia.indiatimes.com/2011-09-20/computing/30179895_1_gamers-enzyme-protease".

AFP Sep 20, 2011, 07.25pm IST

Creative and cool :cool:, simply outstanding...
Online gamers have achieved a feat beyond the realm of Second Life or Dungeons and Dragons: they have deciphered the structure of an enzyme of an AIDS-like virus that had thwarted scientists for a decade.

The exploit is published on Sunday in journal Nature Structural & Molecular Biology , where — exceptionally in scientific publishing — both gamers and researchers are honoured as co-authors.

But a microscope gives only a flat image of what to the outsider looks like a plate of one-dimensional scrunched-up spaghetti and researchers needed a 3D look.

This is where Foldit comes in. Developed in 2008 by the University of Washington, it is a fun-for-purpose video game in which gamers compete to unfold chains of amino acids.

To the astonishment of the scientists, the gamers produced an accurate model of the enzyme in just three weeks. Cracking the enzyme "provides new insights for the design of antiretroviral drugs" , says the study.

Firas Khatib of the university's biochemistry lab said, "The ingenuity of game players is a formidable force that can be used to solve a lot of scientific problems." One of Foldit's creators, Seth Cooper, explained why gamers had succeeded.

"People have spatial reasoning skills, something computers are not yet good at," he said. "Games provide a framework for bringing together the strengths of computers and humans. The results in this week's paper show that gaming, science and computation can be combined to make advances that were not possible before.

Rhody... :approve:
 
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  • #3
The paper can be downloaded directly from the Baker Lab website: http://www.cs.washington.edu/homes/zoran/NSMBfoldit-2011.pdf

Here's a nice writeup describing what the paper is about in fairly clear language (from a person who is both a gamer and a scientist): http://conflux.mwclarkson.com/2011/09/foldit-pmv-pr/
 
  • #4
Outstanding. I remember reading an idea like this in a science fiction book in my teens!
 
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I find this collaboration between gamers and researchers to be incredibly innovative and exciting. The fact that gamers were able to solve a complex scientific problem in just three weeks demonstrates the power of utilizing different skill sets and perspectives in scientific research. It also highlights the potential for using gaming as a tool for scientific discovery and problem-solving.

This achievement also emphasizes the importance of incorporating creativity and out-of-the-box thinking in the scientific process. The gamers' spatial reasoning skills and ability to approach problems from a different angle proved to be a valuable asset in this study.

Furthermore, this collaboration highlights the potential for citizen science, where non-scientists can contribute to scientific research in meaningful ways. It is a great example of how science can be made more accessible and engaging to the general public.

Overall, this study is a testament to the power of combining different disciplines and utilizing new methods in scientific research. It opens up new possibilities for solving complex problems and advancing our understanding of the world around us.
 

1. What is the impact of computer gamers on scientific research?

Computer gamers have had a significant impact on scientific research in recent years. Their passion for technology and problem-solving has led to the development of new tools and methods in research, such as using virtual reality for data visualization and simulation. Gamers also contribute to citizen science projects, where they can help analyze large data sets and contribute to scientific discoveries.

2. Can video games actually improve cognitive abilities?

There is growing evidence that certain video games can improve cognitive abilities, such as spatial reasoning, problem-solving, and decision-making. These games require players to think critically and strategically, which can transfer to real-world situations. However, more research is needed to fully understand the effects of video games on cognitive abilities.

3. How can video games be used for educational purposes?

Video games have been used for educational purposes in various fields, such as medicine, engineering, and environmental science. They can provide interactive and engaging learning experiences, allowing students to apply their knowledge in a simulated environment. Additionally, video games can also be used to teach coding and programming skills, which are increasingly important in the modern workforce.

4. Are there any potential negative effects of video games on individuals?

While there are many potential benefits of video games, there are also some negative effects that have been reported. These include increased aggression and addictive behaviors, as well as potential impacts on mental health and social skills. It is important for individuals to maintain a healthy balance and for parents to monitor their children's gaming habits.

5. How can scientists and gamers collaborate to further scientific research?

Scientists and gamers can collaborate in various ways, such as through citizen science projects, where gamers can contribute to data analysis and help solve scientific problems. Additionally, scientists can work with game developers to create educational and research-based games that can further scientific understanding. It is important for both parties to communicate and find common ground for successful collaborations.

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