- #1
Pythagorean
Gold Member
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Is transgene only a statement of the history of a gene (that it did not develop through selection in the organism)
OR
is a transgene mechanistically different (i.e, does the transgene embed itself into the genome of the host organism and from then on act as if it were any other gene in the DNA strand or does it have a different way of being picked up and used in translation?)
I'm thinking of vectors now, specifically. Do vectors incorporate into the host organisms's DNA before being used? Are they then there forever (I understand that they're likely not in the sex cells, so the phenotype will not get passed on to progeny) in the organism?
Or do vectors float around in the cell and get used by Ribosomes for translation independent of the host organism's main DNA processes?
OR
is a transgene mechanistically different (i.e, does the transgene embed itself into the genome of the host organism and from then on act as if it were any other gene in the DNA strand or does it have a different way of being picked up and used in translation?)
I'm thinking of vectors now, specifically. Do vectors incorporate into the host organisms's DNA before being used? Are they then there forever (I understand that they're likely not in the sex cells, so the phenotype will not get passed on to progeny) in the organism?
Or do vectors float around in the cell and get used by Ribosomes for translation independent of the host organism's main DNA processes?