Is the Immune Response to Nickel Metal Responsible for Nickel Allergies?

  • Thread starter praeclarum
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In summary, nickel allergy is a common allergy that causes contact dermatitis. This is due to an immune response triggered by nickel salts that are formed when in contact with sweat and jewelry or watches. This reaction is often accompanied by corrosion of the object.
  • #1
praeclarum
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Nickel allergy is a very common allergy. It causes contact dermatitis. But why is it allergenic, being a metal. Recall that allergies are caused by an immune response. What exactly are you reacting to -- the nickel metal itself??
 
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  • #2
Well a quick Google turns up this:
http://corrosion-doctors.org/Allergies/images/Pierced.jpg

Sorry, I meant this:

In fact the allergy is not caused by nickel itself but by the nickel salts which are formed under the effect of perspiration in contact with the piece of jewellery piece or watch. This phenomenon is always accompanied by corrosion of the object.
http://corrosion-doctors.org/Allergies/nickelallergy.htm
 
  • #3
Interesting! Thank you.
 

1. Why is nickel allergenic?

Nickel is considered allergenic because it is a metal that is commonly used in alloys and has the ability to cause contact dermatitis, an allergic reaction on the skin.

2. How does nickel cause an allergic reaction?

Nickel ions are released from metal objects when they come into contact with sweat or moisture on the skin. These ions can penetrate the skin and bind to proteins, triggering an immune response in some individuals.

3. Who is most likely to develop a nickel allergy?

People who are frequently exposed to nickel, such as those who work in industries that use nickel, are more likely to develop an allergy. Women are also more likely to have nickel allergies due to their higher rates of metal jewelry use.

4. Can a nickel allergy be prevented?

Although there is no way to prevent a nickel allergy, avoiding contact with nickel-containing objects can help reduce the risk of developing an allergy. This includes avoiding jewelry, watches, and clothing with nickel components.

5. How is a nickel allergy diagnosed and treated?

A nickel allergy can be diagnosed by a skin patch test performed by a dermatologist. Treatment typically involves avoiding nickel exposure and using topical corticosteroids to relieve symptoms. In severe cases, oral antihistamines or immunosuppressant medications may be prescribed.

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