- #1
jayadds
- 42
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Hi all,
I was just wondering, does the ionised form of a drug produce a pharmacological effect? I know that an ionised drug is lipid-insoluble so it cannot traverse across the membrane. However, my question is, what happens to them if they remain in the gastrointestinal tract? Does it still have a function or is it eliminated from the system?
Many thanks,
Jay
I was just wondering, does the ionised form of a drug produce a pharmacological effect? I know that an ionised drug is lipid-insoluble so it cannot traverse across the membrane. However, my question is, what happens to them if they remain in the gastrointestinal tract? Does it still have a function or is it eliminated from the system?
Many thanks,
Jay