New Reply

Leading and lagging strands?

 
Share Thread Thread Tools
Nov18-12, 07:14 AM   #1
 

Leading and lagging strands?


I'm confused regarding one aspect concerning the leading and the lagging strands. Are they the strands which were present before replication occurs (i.e. the original/parent strands) or are they the strands which come into being after replication is completed (i.e. the newly synthesized/daughter strands).

Note:- I understand the 5' to 3' and vice versa distinctions/definitions of the two so don't explain in terms of that.
PhysOrg.com
PhysOrg
biology news on PhysOrg.com

>> Encouraging signs for bee biodiversity
>> Scientists present new insights on climate change and species interactions
>> Bird's playlist could signal mental strengths and weaknesses
Nov18-12, 09:36 AM   #2
 
Recognitions:
Science Advisor Science Advisor
Usually the daughter strands (but the terminology is not so fixed that you can't say "leading strand replication" or "leading parent strand" or "leading template strand").

http://www.ncbi.nlm.nih.gov/books/NBK26850/ (Fig. 5.8)
http://www.ncbi.nlm.nih.gov/books/NBK21751/ (Fig. 12.9)
Nov18-12, 11:26 AM   #3
 
Recognitions:
Science Advisor Science Advisor
As atyy said, "leading" and "lagging" refer to the daughter strands. This is in part because the parent strand can template both leading and lagging strand synthesis. For example, consider a replication bubble. On the side of the bubble, the left side of the bubble, the top parent strand acts as the template for leading strand synthesis while on the right, the same parent strand acts as the template for lagging strand synthesis.
Nov18-12, 09:24 PM   #4
 

Leading and lagging strands?


That cleared up any confusion I had. Thanks.
New Reply
Thread Tools


Similar Threads for: Leading and lagging strands?
Thread Forum Replies
Physical Meaning of Leading/Lagging Voltage/Current Electrical Engineering 38
Leading and Lagging voltages Introductory Physics Homework 1
Leading/Lagging and Phasors Engineering, Comp Sci, & Technology Homework 2
current/voltage leading and lagging Electrical Engineering 4
lagging and leading Engineering, Comp Sci, & Technology Homework 2