IGF-1 stands for Insulin-like Growth Factor 1, which is a protein hormone that plays a crucial role in cell growth and development.
IGF-1 binds to specific receptors on the surface of cells and activates a signaling pathway that promotes cell growth and division. It also stimulates the production of other growth factors and regulates cell survival and metabolism.
IGF-1 is essential for normal growth and development, particularly during childhood and adolescence. It also helps maintain tissue and organ function in adults, and plays a role in wound healing and tissue repair.
High levels of IGF-1 have been linked to increased cell proliferation and growth, which can lead to an increased risk of cancer. It has also been associated with conditions such as acromegaly and gigantism, where there is excessive growth of bones and tissues.
IGF-1 levels are primarily regulated by growth hormone, which is produced by the pituitary gland. Other factors, such as nutrition, exercise, and stress, can also affect IGF-1 levels. Certain medications and medical conditions can also impact IGF-1 production and signaling.