Ultrasound and DNA repair


by TheAlkemist
Tags: repair, ultrasound
TheAlkemist
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#1
Aug27-09, 10:03 PM
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Is there any SCIENTIFIC evidence of the effect of ultrasound on chemical repair of DNA? As in, is there peer-reviewed research in this?

Thanks.
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jim mcnamara
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Aug28-09, 07:13 AM
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This atricle shows that a chemotherapy-resistant ovarian cancer cell line ( because of DNA repair) becomes less resistant on exposure to ultrasound.

http://www.ingentaconnect.com/conten...00003/art00017
Andy Resnick
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Aug28-09, 07:49 AM
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I couldn't read the whole article, just the abstract, but it doesn't make any sense. Ultrasound (MHz) has wavelengths in the millimeter range- how can targeted subcellular damage occur?

The abstract also did not mention the incident energy level, but I suspect it's much lower than occurs with UV damage.

TheAlkemist
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#4
Aug28-09, 12:34 PM
P: 97

Ultrasound and DNA repair


Thanks for the link Jim. I can't access the full article, but if you can, could you address Andy's question? I'm curious.
Thanks :)
Monique
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#5
Aug29-09, 09:11 AM
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Quote Quote by Andy Resnick View Post
I couldn't read the whole article, just the abstract, but it doesn't make any sense. Ultrasound (MHz) has wavelengths in the millimeter range- how can targeted subcellular damage occur?

The abstract also did not mention the incident energy level, but I suspect it's much lower than occurs with UV damage.
According to the introduction the ultrasound treatment leads to increased intracellular drug levels, I haven't read the study so I can't comment on the validity.


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