The limitations of RP-HPLC

by Shaybay92
Tags: chemical analysis, hplc, limitations, organic chemistry, rp-hplc
Shaybay92 is offline
Aug29-09, 05:49 AM
P: 122
As HPLC is such a common method in chemical analysis, I was just wondering what are the limitations to such a technique? What compounds/mixtures is it limited to analyzing?
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chemisttree is offline
Sep5-09, 09:16 AM
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Well it certainly is limited to the analysis of compounds which are soluble in the mobile phase. It is limited to the analysis of compounds which are not reactive with the mobile phase or stationary phase as well.

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