
#1
Jun3012, 09:37 AM

P: 1

I have survival and other data for between ~1000 patients from different studies with indications varying from organ transplantation to cancer. Patients within this cohort will have been drawn from many different studies in which the objective  longterm graft survival, overall survival rate, metatstasis free survival, organ acute rejection rate, graft loss, etc.  was different. I want to essentially control for all the variables of disease (cancer, organ disease and severity), sex, age, etc. to find out the effect of one explanatory variable  use of drug X as opposed to drugs Y, Z, etc.  on survival/time to death of patients. In the case of organ transplantation, drug X is used as an immunosuppressant: it's primary objective is not to treat disease as such. In the case of the cancer studies however, drug X has a curative objective.
How can I test drug X's effect on only survival within this cohort? 


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