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Competitive antagonism in Schild plot 
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#1
Jul1613, 12:05 AM

P: 42

Hi all,
I was just wondering, why is the slope of the Schild plot equal to 1 when competitive antagonism occurs? If possible, can you please explain it by relating to the equation: log(r1) = logx  logK where r = dose ratio, x = antagonist concentratoin and K = dissociation constant Many thanks, Jay 


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