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2 male -> 1 female?

  1. Jul 16, 2006 #1
    Alright you have 2 male stem cells.
    You have 1 through 22 chromosomes
    X and Y.

    Now you take the first stem cell you leave the 1-22 chromosomes alone. You leave the one X alone and get rid of the Y. You then goto the second stem cell ignore the 1 through 22 chromosomes and the Y. But steal the X. You then move that stolen X into the Y chromosome's spot in stem cell #1.

    Now I'm not sure if the 2 male stem cells should be exactly the same source or well not. Obviously it doesn't have to be human stem cells. I just don't know how many stem cells are in mice or pigs or whatever the alternative in animals would be.

    Now my questions are: has it been done before? can it be done(science advanced enough?legal issues?)? what would the result's be?

    Say you were to use identical stem cells from the same source. Wouldn't it be possible to grow a male version and then the female duplicate? Would this essentially be identical twins which are female and male(isn't this usually a klinefelters syndrome problem though, rather then like what I am suggesting?)
  2. jcsd
  3. Jul 16, 2006 #2
    Hardly possible. When a cell is no dividing, there is no chromosomes. The DNA is just loose in the nucleus.
  4. Jul 16, 2006 #3
    Well I'm saying doing this in the most advanced lab which can manipulate to do whatever is necessary.
  5. Jul 16, 2006 #4
    Now we are getting too metaphysical for my taste. If you are in 'the most advanced lab' then you could do this (even if in reality it wouldn't work).

    Or do you mean if the hole creating a female from two men is possible if we set aside the extration?

    Seriously, you could just use this 'advanced lab' to do the impossible.

    I find your question a bit odd.

    So you want to know if it would be theoretically possible?
  6. Jul 17, 2006 #5
    Indeeed. If it is, what would it result?

    well the most advanced lab being like the WHO or the ivy league universities.
  7. Jul 17, 2006 #6
    There is currently no lab in the world that is able to extract what you are talking about.

    If you had a lab that could do that, that lab would also be able to do other impossible things.

    You cannot simply bypass one part of it and say "whatif?". What you are asking is not possible. It is just crackpot science in my opinion.
  8. Jul 19, 2006 #7


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    Staff Emeritus
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    Gold Member

    Don't be so quick to judge, labs can do some very advanced things so there'll probably be a solution for the problem if you think long enough. If you really want to do the experiment (whether it is of any use) is another issue.

    Scientists have created mice and worm strains, where each animal carries a chromosome from another species. So let's take C. elegans for example. You'll have a worm strain that carries autosome 2-5 from the N2 strain and autosome 1 from the Hawaiien strain. Another worm strain carries autosome 1,3-5 of N2 and autosome 2 of Hawaiien, etc. What do you think of that?
  9. Jul 19, 2006 #8
    It is pretty interesting, but that it is a long way to entire genomes. Other similar examples to the subject as a whole is the golden rice and other gene-modified plants and animals.

    Perhaps we wouldn't even need to remove the unwanted DNA? We could just deactivate it and hope that it does not disturb the other reactions. That has worked in the past, both via manipulation and naturally for the matter although in small scale. It would simple be a question of finding the right combination of components to do so.

    Another ways is creating a small suction device. After all, we have instruments that are fit for cellular level, so why not nucleus level? To find the right DNA to remove, we could radiation, electromagnetism and so on as the field on nanotechnology predicts a pretty advanced future.

    As demonstrated above, there is a fine line between plausible applications and random speculations of what might be possible in an unforeseeable future even if there have been some limited progress in that particular field.
  10. Jul 19, 2006 #9

    jim mcnamara

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    Staff: Mentor

    Point: stem cells are diploid. They have 2N chromosomes.
    That measn there are (22+1) * 2 = 46 chromosomes.
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