In the interest of Biochemisty I sat through an infomercial about a new weight-loss pill: Satise. This pill claims to contains a protein derived from a potato which promotes satiety (hence the name) thus affecting weight loss. The infomercial mentioned cholecystokinin (rather quickly). Cholecystokinin is normally secreted from the small intestines in the presence of partially digested fats and proteins. This in turns stimulates the pancreas and gallbladder to deliver digestive enzymes. It, in conjunction with leptin, also affects neurons in the brain to promote satiety. Wouldn't stomach acids break up ingested cholecystokinin before it can affect the pancreas and gall bladder? I don't think Satise works for this reason but I could be wrong. Ummmm . . . my turkey's startin' to smell good . . .