1. Limited time only! Sign up for a free 30min personal tutor trial with Chegg Tutors
    Dismiss Notice
Dismiss Notice
Join Physics Forums Today!
The friendliest, high quality science and math community on the planet! Everyone who loves science is here!

Homework Help: Acetic acid to propanoic acid

  1. Mar 4, 2013 #1
    Without using a cyanide
  2. jcsd
  3. Mar 5, 2013 #2
    What other methods of chain homologation do you know?
  4. Mar 5, 2013 #3
    i was thinking of acetyl chloride and then N-methylethanamide... that will give me 3 carbons... but then how to get rid of nitrogen and bring OH?
  5. Mar 6, 2013 #4
    Can you draw some structures? Seems like N-methylacetamide has the wrong carbon backbone too.
  6. Mar 6, 2013 #5
    yeah... that's where i'm stuck... i really have no idea on how to bring the carbon inside!!

    how about this:
    acetyl chloride then diazoketone then wolff rearrangement and then water! right?
    Last edited: Mar 6, 2013
Share this great discussion with others via Reddit, Google+, Twitter, or Facebook

Have something to add?
Draft saved Draft deleted