Dismiss Notice
Join Physics Forums Today!
The friendliest, high quality science and math community on the planet! Everyone who loves science is here!

Action of Salicylic Acid

  1. Jul 5, 2011 #1
    Hi guys, I just have a quick query about the mechanism of action of salicylic acid. I have tried in vain to find a solution elsewhere, but have not had any luck.

    How exactly does salicyclic acid work. As far as I can tell, it doesn't have an acetyl group, which is how aspirin mediates its effects on COX. However, my research seem to suggest that this is the active form of aspirin (ie. Aspirin undergoes hydrolysis to salicylic acid prior to acetalysing COX). Is this true, and if so, how does it work?

    Kind Regards.
  2. jcsd
  3. Jul 7, 2011 #2


    User Avatar
    Science Advisor
    Homework Helper
    Gold Member

    You need to alter your understanding of aspirin's mechanism of action perhaps.

  4. Jul 11, 2011 #3
    Thanks very much - It seems i need to reevaluate my understanding of its action.
Share this great discussion with others via Reddit, Google+, Twitter, or Facebook