- #1
mesna
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Hello friends!
I have a query for which i have been trying to find an answer for a long time but in vain!
Can anybody tell me how do we find the effect of pH on amphoteric compounds?I am currently working on Amphotericin B which happens to have both the acidic and the amino groups. I need to know how such compounds would behave in solutions with different pH values, especially physiological pH. (The -COOH pka is 5.7 and the -NH2 pka is 10.0).
I would be really really grateful if some1 could answer this question!
Thanks a ton!
Mesna
I have a query for which i have been trying to find an answer for a long time but in vain!
Can anybody tell me how do we find the effect of pH on amphoteric compounds?I am currently working on Amphotericin B which happens to have both the acidic and the amino groups. I need to know how such compounds would behave in solutions with different pH values, especially physiological pH. (The -COOH pka is 5.7 and the -NH2 pka is 10.0).
I would be really really grateful if some1 could answer this question!
Thanks a ton!
Mesna