In combat sports there is a fight-ending strike (punch or kick) called the liver strike (or liver shot / liver kick). Basically it's a punch (or kick) aimed below the right pectoral muscle into the area where the liver is located. When it hits, the fighter experiences excruciating pain, and usually falls to the floor into a fetal position. The pain is described as a debilitating burning sensation, accompanied by a complete loss of breath. There does not seem to be any permanent damage, as the fighters are usually able to stand back up within minutes. What is the physiological cause for the intense pain? Does it have something to do with the vagus nerve plexus? Due to my low postcount i can't post URL links to fights with liver strikes. But you can see a couple on Youtube by looking for "Filipovic vs Magomedov" or "Gono vs. Salaverry".