Bio-Engineering Advances

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In summary, new approaches to treat diseases include in vivo gene editing in monkeys to reduce liver protein and improve cardiac health, as well as mitochondrial transplant to damaged infant heart tissue. This technique involves injecting undamaged mitochondria from other parts of the body into the damaged heart cells, providing them with functional energy sources and improving heart output. This method has been successful in improving cardiac health and has also been used in embryos to prevent transmission of genetic diseases.
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BillTre
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New approaches to treat diseases:

In vivo
(In the living animal) gene editing in monkeys reduces a liver protein, lowering cholesterol levels to improve cardiac health.
About 60% of the cells in the liver were effected, an impressive percentage.
Science mag news article here.

Mitochondrial transplant to damaged infant heart tissue.
Mitochondrial can get damaged and/or killed, leaving the cells alive but not very functional (not good for heart cells).
Undamaged mitochondrial from OK parts of the injured party's body (eliminating the possibility of immune rejection) are isolated and injected into a mass of injured cardiac muscle cells.
The [URL="https://www.physicsforums.com/insights/when-did-mitochondria-evolve/"]mitochondria[/URL] (a cellular organelle, much larger than a molecule, more like a bacteria, with their own mini-genome) get into the cells (by means unknown to me,) and provide the cell with much more functional energy sources than the damaged mitocondria.
Cells get better, improving heart output.
This also requires effecting a decent percentage of the target cells (thousands to millions), in a tissue (lots of structure and diffusion barriers (especially for large particles)).
https://www.nytimes.com/2018/07/10/health/https://www.physicsforums.com/insights/when-did-mitochondria-evolve/-transplant-heart-attack.html?em_pos=large&emc=edit_sc_20180710&nl=science-times&nlid=38810697edit_sc_20180710&ref=headline&te=1.
 
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What is bio-engineering?

Bio-engineering is the application of engineering principles to biological systems and processes in order to develop new technologies and products. It involves manipulating living organisms or their components to create useful products or solve problems in various fields, such as healthcare, agriculture, and environmental conservation.

What are some recent advances in bio-engineering?

Some recent bio-engineering advances include the development of gene editing technologies like CRISPR, 3D bioprinting, and the use of stem cells for regenerative medicine. Other notable advancements include the creation of biodegradable materials and the use of synthetic biology to create new organisms with specific functions.

How is bio-engineering used in healthcare?

Bio-engineering has a wide range of applications in healthcare, such as developing new drugs and therapies, creating medical devices and implants, and improving diagnostic techniques. It is also used in tissue engineering and regenerative medicine to create replacement tissues and organs for patients.

What are the ethical considerations in bio-engineering?

As with any rapidly advancing technology, there are ethical concerns surrounding bio-engineering. These include issues of safety, equity, and the manipulation of natural systems. There are also questions about the potential consequences of genetically modifying organisms and the impact on society as a whole.

What is the future of bio-engineering?

The future of bio-engineering is exciting, with the potential to revolutionize various industries and solve many global challenges. Some potential advancements include personalized medicine tailored to an individual's genetic makeup, environmentally friendly solutions for food production, and the development of sustainable biomaterials. However, it is important to carefully consider the potential risks and ethical implications as we continue to push the boundaries of bio-engineering.

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