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Biochemistry (Nucleotide Polymerization)
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[QUOTE="Drakkith, post: 6837262, member: 272035"] I'm not an expert in this area, but I did find this source:[URL]https://casegroup.rutgers.edu/lnotes/dnab.pdf[/URL] See slide 23 where it says: [I]The two types of sugar pucker most commonly found in nucleic acids. The C3′-endo pucker is prevalent in RNA and A-form DNA, whereas the C2′-endo pucker is characteristic of B-form DNA. It is seen that the C3′-endo pucker produces a significantly shorter phosphate-phosphate distance in the backbone, resulting in a more compact helical conformation.[/I] I wish I could help you more. I believe the hydroxyl is located on the 3' end of the DNA or RNA molecule. The triphosphate bonds where the hydroxyl is, turning it into a pyrophosphate since one of the phosphates stays bound between the two nucleotides while the other two are freed. [/QUOTE]
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