1. Not finding help here? Sign up for a free 30min tutor trial with Chegg Tutors
    Dismiss Notice
Dismiss Notice
Join Physics Forums Today!
The friendliest, high quality science and math community on the planet! Everyone who loves science is here!

[Biology]Orientation of microtubules

  1. Mar 24, 2008 #1
    1. The problem statement, all variables and given/known data
    1. Because cytoplasmic vesicles are seen to move in both directions in the axon of a nerve cell, can you conclude that some of the microtubules are orientated with their plus-end facing the axon terminus and others orientated with the opposite polarity? Why or why not?

    2. Relevant equations

    3. The attempt at a solution
    The positive end is designated for the addition of actin subunits, where the ATP-binding cleft of the terminal actin subunit contacts the neighboring subunit (barbed). The negative end is favored for dissociation, where the cleft is exposed to the surrounding solution. Since the cleft is exposed, ATP will bind, hydrolysis of the bound nucleotide reduces the affinity of the subunit for neighboring subunit, and therefore the negative end is favored for dissociation.
  2. jcsd
Know someone interested in this topic? Share this thread via Reddit, Google+, Twitter, or Facebook

Can you help with the solution or looking for help too?

Similar Discussions: [Biology]Orientation of microtubules
  1. Biology question (Replies: 0)