I have been looking for biomarkers for Alzheimer's disease which can be detected in structural MRI. I have gone through some papers and found that Gray matter, white matter and CSF are good biomarkers. But is there any other except?
That's good. But is there any relation between GM, WM and CSF changes for alzheimer's. Like after processing the MRI images and extracting these features from them, is there any kind of relation among these which can collectively be used to say that "yes this image is having alzheimer's".Gray matter, white matter and CSF are the main components of the brain and probably encompass most of the structures of the brain that you could examine by structural MRI.
From: https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/in-depth/alzheimers/art-20048075Alzheimer's dementia results from the progressive loss (degeneration) of brain cells. This degeneration may show up in a variety of ways in brain scans.
However, these scans alone aren't enough to make a diagnosis.