• Support PF! Buy your school textbooks, materials and every day products Here!

Biophysics - DNA Polymerase

  • #1
Greetings all,

I have a problem where I am asked to estimate the number of DNA polymerase in a eukaryotic cell. The sub-question prior to this asked me to find what fraction of the total DNA of a fly was shown in a micrograph in my book.

How do I go about estimating this? Is it 2 for each "loop" ?
 

Answers and Replies

  • #2
yowza
 
  • #3
Ygggdrasil
Science Advisor
Insights Author
Gold Member
2019 Award
3,024
2,631
One way to go about making some guess at this number would be to calculate the minimum number of polymerase molecules to copy the entire genome in the span of the doubling time (or the length of the S-phase for eukaryotes). For this, you would need to know the amount of time that the cell has to replicate its DNA, the average speed at which a DNA polymerase can synthesize DNA, and the size of the genome.
 

Related Threads on Biophysics - DNA Polymerase

Replies
1
Views
10K
  • Last Post
Replies
3
Views
2K
  • Last Post
Replies
6
Views
2K
  • Last Post
Replies
1
Views
802
  • Last Post
Replies
3
Views
2K
  • Last Post
Replies
1
Views
3K
  • Last Post
Replies
13
Views
8K
  • Last Post
Replies
1
Views
1K
  • Last Post
Replies
7
Views
21K
  • Last Post
Replies
0
Views
1K
Top