So I know that the dose-dependent toxicity of a substance is often in a way such that very small doses are more harmful than small doses since a sort of tolerance develops once the body senses small doses of the substance. But does this tolerance develop for GENOTOXIC effects with respect to a lot of substances? (of course, damage is often good enough to increase one's risks of cancer). And back to the topic question - does this tolerance develop for gasoline, something that most of us are exposed to on a daily basis? It seems that a lot of people have to deal with gasoline as part of their lives.