1. PF Contest - Win "Conquering the Physics GRE" book! Click Here to Enter
    Dismiss Notice
Dismiss Notice
Join Physics Forums Today!
The friendliest, high quality science and math community on the planet! Everyone who loves science is here!

Chemistry - Edman degradation

  1. Jan 12, 2009 #1
    I'm looking at a (uni) past paper and it has one of those typical Qs - a molecular weight determination has shown that an unknown peptide E is a pentapeptide and that it contains the amino acids glycine, tryptophan, proline, valine and alanine. Treatment of pentapeptide E with carboxypeptidase gives proline as the first free amino acid released. Separate Edman degradations provided the following derivatives: and it shows three compounds, with the first containing tryptophan, second just glycine, third valine.
    Based upon this analysis, draw the structure of the original pentapeptide and explain how you have arrived at this structure. Show mechanistic detail where appropriate (15 marks).

    Anyone know?
  2. jcsd
  3. Jan 12, 2009 #2


    User Avatar
    Science Advisor
    Homework Helper
    Gold Member

    Which flavor of Carboxypeptidase are you using? "Separate Edman degradations..." refers to what?
  4. Jan 12, 2009 #3
    what flavor???
Know someone interested in this topic? Share this thread via Reddit, Google+, Twitter, or Facebook

Similar Threads - Chemistry Edman degradation Date
Determination of an Acid (Monoprotic) by Titration Lab Thursday at 3:48 PM
Chemistry Heat Flow Question Jan 29, 2018
Help Naming Hydrocarbons Jan 6, 2018
Final temperature of the water after adding heat? Jan 4, 2018