Can anyone hook me up with some good sites that describe the science behind how cocaine affects the human nervous system? I've searched by found little quality I'll be grateful is you can procide me with any sites/info.
Amphetamines and cocaine bind to — thus blocking — transporters used for the reuptake of dopamine (and noradrenaline) into presynaptic neurons. This causes the level of dopamine to rise in the synapses. High levels of dopamine in an area of the brain called the nucleus accumbens appear to mediate the pleasurable effects associated with these (as well as other) psychoactive drugs.