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DNA Replication

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  1. Apr 24, 2012 #1
    Before I ask my question, I would like to state that I am not a Biology student. I am actually a Chemistry student who has a small section on Biochemistry in his syllabus.

    Now, my problem lies with part (ii).

    Mechloroethamine obviously hold the DNA strands together and prevents the DNA helix from uncurling/unzipping. Hence, the very first stage in replication is impeded.

    How cis-platin affects DNA replication is eluding me. I know that Guanine normally forms 3 hydrogen bonds with Cytosine. However, it seems to be forming only one hydrogen bond in this case.

    Could someone prod me in the correct direction ?
     

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  2. jcsd
  3. Apr 24, 2012 #2
  4. Apr 24, 2012 #3
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