Me: double major in applied math. and neuroscience at a big research school. I want to do research (always have) and I have to decided what Grad. school to go to and what typed of research I want to get into. I think I want to do computational neuroscience -- it's the only way I see (in conjunction with molecular & systems neuroscience) to understand how brains really work. The problem, however, is that there is a long history of the life sciences fumbling with math. -- largely in an attempt to become "legitimate" in the eyes of the physical sciences. Biological systems are so breathtakingly complicated it is often hard to make accurate mathmatical models of them -- yet we get maligned when we fail to model 200 billion brain cells accurately or put epigenetics into an equation. "Biology is basically arts -- not science" is a phrase that I've often encounter with people in the math department. Anyway, constantly hearing that has an impact. In a way, it kind of stings... Getting higher grades than the physics majors in my math classes and roommates in engineering only shuts them up. Of course, they still believe what they always have...Some people just love being ignorant and wrong. Yet, I've internalized that ignorance. In short, my problem is: do I want to do computational neuro., or am I doing trying to appease the physical science people? That is what I am trying to understand... Has anyone out there experienced similar confusions regarding their motivations for their career goals?