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Drug target ?

  1. Mar 22, 2004 #1
    Drug target ??

    I've got a protein produced by pathogens and i've got its sequence.
    How would i know whether it can be a potential Drug target ....
     
  2. jcsd
  3. Mar 22, 2004 #2

    iansmith

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    You should do a BLASTP search at http://www.ncbi.nlm.nih.gov/BLAST/
    This will give you homologue of you sequence and will give you a possible function including the target. The next step migth be to look for specific pattern at http://ca.expasy.org/tools/scanprosite/

    Once you think you migth have a good target you can then do solid phase binding assays and affinity isolation.
     
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