The problem asks to consider the following reaction: S + E =ES1=ES2---> P + E where = between S + E and ES1 has a forward reaction constant of k1 and a reverse constant of K2. The = between ES1 and ES2 has a forward reaction of k3 and a reverse of k4 and ----> has a k5 forward reaction constant. I need to solve for ES2 to plug into the equation v=k5[ES2]. I am having a lot of trouble finding Km which is the Michaelis-Menton Constant. Any help would be greatly appreciated.