As I know chemical potential of two reacting substances strongly depends on difference in Fermi energy between them. Fermi energy is inversely proportional to the mass of particles. Does that mean that Fermi energy of bare proton will be 2000 time smaller than that of electron? Usually nuclei energy do not participate in chemical reactions. But what about bare protons?They could be captured by atoms sometimes and form some intercalated compounds. Do exist some chemical reactions in which tremedious difference in Fermi energy of electrons and bare protons shows up with great energy excess?