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Freebases and HCL salts

  1. Jan 11, 2004 #1

    Certain drugs need to be freebased, can someone explain this (the meaning of freebaing)? Why would you want to freebase?
    I believe that when they are freebased they form a salt of HCL or something, what's with that? Is it analogous to hydrated salt, where a compound can hold like 2 moles of water within its structure? Why HCl?
  2. jcsd
  3. Jan 11, 2004 #2
    A lot of drugs have an amine group that acts like a base. The base reacts with an acid (HCl) to form a salt, the salt is the freebase. THis is advantageous because then you'll have a solid chemical as opposed to the oilly garbage that is the base form.
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