Haldane's Dilemma (1 Viewer)

Users Who Are Viewing This Thread (Users: 0, Guests: 1)

This paper states that rates of beneficial mutations can not account for the time that has passed between the first homonids and humans. Has this been resolved? How?


I think this statement on the wiki page sums it up "The neutrality and factual accuracy of this article are disputed."

The rebutal - "Haldane's "cost of natural selection" stemmed from an invalid simplifying assumption in his calculations. He divided by a fitness constant in a way that invalidated his assumption of constant population size, and his cost of selection is an artifact of the changed population size. He also assumed that two mutations would take twice as long to reach fixation as one, but because of sexual recombination, the two can be selected simultaneously and both reach fixation sooner. With corrected calculations, the cost disappears (Wallace 1991; Williams n.d.). "


The Physics Forums Way

We Value Quality
• Topics based on mainstream science
• Proper English grammar and spelling
We Value Civility
• Positive and compassionate attitudes
• Patience while debating
We Value Productivity
• Disciplined to remain on-topic
• Recognition of own weaknesses
• Solo and co-op problem solving