- #1
- 3,759
- 4,199
Today (AUG 1) is RNA Day, an international celebration of one of the most versatile biomolecules in existence. This year, in particular, we are reminded of the importance of RNA biology as a pandemic caused by an RNA virus has disrupted life worldwide.
What are some areas of RNA research that excite you most? Here are some recent papers/topics on RNA biology that have been on my mind recently:
Targeting PTBP1, an RNA binding protein, could help regenerate neurons:
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice
Reversing a model of Parkinson’s disease with in situ converted nigral neurons
The role of R-loops (formed by the hybridization of mRNA and DNA at transcription bubbles) in regulating transcription and genome stability:
Regulatory R-loops as facilitators of gene expression and genome stability
R-loops coordinate with SOX2 in regulating reprogramming to pluripotency
RNA modifications can regulate transcription through regulation of chromatin-associated regulatory RNAs:
N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
(Here's the link to last year's RNA day thread with more good reading: https://www.physicsforums.com/threads/happy-rna-day.952500/)
What are some areas of RNA research that excite you most? Here are some recent papers/topics on RNA biology that have been on my mind recently:
Targeting PTBP1, an RNA binding protein, could help regenerate neurons:
Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice
Reversing a model of Parkinson’s disease with in situ converted nigral neurons
The role of R-loops (formed by the hybridization of mRNA and DNA at transcription bubbles) in regulating transcription and genome stability:
Regulatory R-loops as facilitators of gene expression and genome stability
R-loops coordinate with SOX2 in regulating reprogramming to pluripotency
RNA modifications can regulate transcription through regulation of chromatin-associated regulatory RNAs:
N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
(Here's the link to last year's RNA day thread with more good reading: https://www.physicsforums.com/threads/happy-rna-day.952500/)