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Hemoglobin and p450 oxygen binding

  1. Nov 21, 2009 #1
    1. The problem statement, all variables and given/known data
    What are the similarities and differences between hemoglobin and cytochrome P-450 involved in dioxygen binding reactions?


    2. Relevant equations



    3. The attempt at a solution
    I've heard that there are catalytic cycle of P-450. But is it related to oxygen binding? Or it is just a process for oxdiation of org. cpds?
    Is the binding of O2 to Fe(II) in hemoglobin a redox reaction? I have checked some website said Fe is oxidized to Fe(III) with oxygen turning into superoxide but some say Fe remains Fe(II) to form dioxygen adduct. Which is true for the case of hemoglobin?

    Thanks!
     
  2. jcsd
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