High pressure chromatography?

  • Thread starter sanjuro
  • Start date
  • #1
sanjuro
10
0
What are the applications and advantages/disdvantages of using gas
and high pressure chromatography? Why does the pharmaceutial industry
use chromatography?

Any info would be much appreciated

Thanx
 
Last edited by a moderator:

Answers and Replies

  • #2
Bystander
Science Advisor
Homework Helper
Gold Member
5,406
1,494
Term paper, huh? Look for "review" articles --- Chemical Review is an obvious first place, then it's off to Chem. Abstracts, or Physics Abstracts.
 
  • #3
Chemicalsuperfreak
225
0
GC and HPLC are great analytical tools. But can't be used for seperation. The pharmaceutical industry hates chromatography with a passion and would much rather take a hit with yield than not running a seperation.
 
  • #4
Originally posted by Chemicalsuperfreak
GC and HPLC are great analytical tools. But can't be used for seperation. The pharmaceutical industry hates chromatography with a passion and would much rather take a hit with yield than not running a seperation.

I don't quite understand, why you even say that they can not be used for seperation. They are not meant for seperating, only for analyzing.

Nautica
 
  • #5
Chemicalsuperfreak
225
0
Originally posted by nautica
I don't quite understand, why you even say that they can not be used for seperation. They are not meant for seperating, only for analyzing.

Nautica

Other forms of chromatography are commonly used for bulk seperation. They all separate of course...
 
  • #6
Bystander
Science Advisor
Homework Helper
Gold Member
5,406
1,494
"Preparative chromatography" produces 2k hits, GC, LC, and HPLC --- analysis rather than separation? Huh? That's the analytical principle --- the separation of components from each other.

Iowa State (?) used to run a commercial separation of lanthanides; this day and age, EPA and OSHA would probably bankrupt you with disposal fees before you could fail gracefully as a consequence of an insufficient market for chromatographic separations --- it's expensive, it's a special case (cost is no object) method, and it's entirely too time consuming for accounting depts/divs.

2k hits? Obviously still around.

Edit: Google math is as peculiar as "new math," 2k = 575 by actual count.
 
Last edited:

Suggested for: High pressure chromatography?

  • Last Post
Replies
3
Views
810
Replies
1
Views
1K
Replies
10
Views
495
Replies
22
Views
185
Replies
8
Views
1K
Replies
5
Views
238
Replies
3
Views
2K
Replies
2
Views
1K
Top