The researchers conducted clinical tests on 40 AIDS patients in the United States.
AK602 not only proved effective against viruses that had become resistant to other drugs, but it also caused almost no side effects, the team said.(IHT/Asahi: July 7,2005)
detta said:CCR5 is a chemokine receptor that is expressed primarily on cells of the immune system (B-cells, T-cells, macrophages). Basically, it is important for the immune response because it helps activate the cells when there is an infection. So what I think this is about is that they found something that blocks the receptor so that HIV doesn't recognize the cell since certain strains of HIV need to recognize this receptor to infect the cell. I'm not sure how novel this idea is since I think other drugs have been made with similar functions but I don't know the specifics. Also, apparently there are other receptors that HIV can recognize although I believe this is the dominant one.
"HIV: Leap or Step?" is a scientific theory that suggests that the Human Immunodeficiency Virus (HIV) evolved from a similar virus in primates and then made a "leap" into humans, rather than slowly adapting over time in a "step"wise manner.
One of the main pieces of evidence for the "leap" theory is the fact that HIV is closely related to a virus found in chimpanzees, called simian immunodeficiency virus (SIV). Additionally, studies have shown that the genetic makeup of HIV is more similar to SIV than to any other virus.
The "serial passage" theory suggests that HIV evolved from a virus that was already present in humans, but underwent multiple mutations and adaptations through repeated transmission between individuals. The "leap" theory, on the other hand, proposes that HIV made a single jump from primates to humans, with minimal genetic changes.
Some scientists argue that the "leap" theory is not supported by the available evidence. They point to the fact that HIV is much more closely related to SIV from chimpanzees than from any other primate, suggesting that the virus may have been transmitted through other species before reaching humans. Additionally, there is no definitive proof that the "leap" occurred in a single event rather than through multiple transmissions.
Understanding the origins and evolution of HIV is important for developing effective treatments and prevention strategies. By studying how the virus evolved, scientists can better understand how it may adapt and change in the future, and how to target and combat it. Additionally, understanding the origins of the virus can help to dispel myths and stigma surrounding HIV and those living with the virus.