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How to dissolve chitosan?

  1. Sep 30, 2011 #1
    I am trying to create a solution of Chitosan (Low MW) in 1% Acetic acid. I ve tried dissolving up to 3gr per 100ml (Literature reports solutions up to 10% wt.)

    My problem is that by using extensive sonication and stirring for days the solution is still very thick (very viscous) and you can see particles in it.

    If I use heating (~70 C for a day) I can get a cleaner (less viscous) solution but strangely the colour changes from light yellow to dark orange. Do i induce somekind of crosslinking that way?

    Whats the safe way to dissolve Chitosan?
  2. jcsd
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