Hydrolysis of Peptide Bonds on Chemsketch

[melissajohn]

I drew this on chemsketch - http://img413.imageshack.us/my.php?image=peptide1kn3.jpg

I am trying to figure out what the results would be... there are 3 peptide bonds here... where would the reaction take place? the first, second or third peptide?

My guess would be that I could do the reaction on any... is that right?

 

[STLCards002]

I'd say the HN=C b/c N is less electronegative than O.

 

[Blueshift5]

The chemsketch drawing you have provided shows three peptide bonds, which are the bonds between the amino acids in a peptide chain. Hydrolysis of peptide bonds is a common biochemical reaction that breaks the bond between two amino acids, resulting in the release of water and the formation of two separate amino acids. In your drawing, the hydrolysis reaction could take place at any of the three peptide bonds, as they are all susceptible to hydrolysis. The specific location of the reaction would depend on the conditions and enzymes present in the reaction. Generally, hydrolysis reactions occur at the weakest bond or the one with the least steric hindrance. Therefore, the reaction could potentially occur at any of the three peptide bonds, but further experimentation would be needed to determine the most likely location of the reaction.